5-Bromo-7-azaindole , 97% , 183208-35-7

Synonym(s):
5-Bromo-1H-pyrrolo[2,3-b]pyridine

CAS NO.：183208-35-7

Empirical Formula: C7H5BrN2

Molecular Weight: 197.03

MDL number: MFCD06659677

EINECS: 629-247-8

PRODUCT Properties

• Melting point: 176-180 °C
• Boiling point: 357.4±42.0 °C(Predicted)
• Density: 1.79±0.1 g/cm3(Predicted)
• storage temp.: Sealed in dry,Room Temperature
• pka: 6.25±0.20(Predicted)
• form: Crystalline Powder
• color: White to yellow
• InChI: InChI=1S/C7H5BrN2/c8-6-3-5-1-2-9-7(5)10-4-6/h1-4H,(H,9,10)
• InChIKey: LPTVWZSQAIDCEB-UHFFFAOYSA-N
• SMILES: C12NC=CC1=CC(Br)=CN=2
• LogP: 1.8 at 25℃ and pH7
• CAS DataBase Reference: 183208-35-7(CAS DataBase Reference)

Description and Uses

5-Bromo-7-azaindole is a chemical reagent used in organic syntheses. Used in the synthesis of Venetoclax (A112430), a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. Also used in other 7-azaindole derivatives such as for PDK1 inihibtors.

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H302-H318
• Precautionary statements: P280-P301+P312+P330-P305+P351+P338+P310
• Hazard Codes: Xi,Xn
• Risk Statements: 22-41
• Safety Statements: 26-39
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 29339900