Home Categories Benzamidine hydrochloride
A1184312

Benzamidine hydrochloride , 98% , 1670-14-0

Synonym(s):
Additive Screening Solution 37/Kit-No 78374;Benzamidine hydrochloride solution;Benzamidine, Hydrochloride - CAS 1670-14-0 - Calbiochem

CAS NO.:1670-14-0

Empirical Formula: C7H9ClN2

Molecular Weight: 156.61

MDL number: MFCD00013025

EINECS: 216-795-4

Pack Size Price Stock Quantity
5G RMB32.00 In Stock
25G RMB84.00 In Stock
100G RMB103.20 In Stock
500G RMB388.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 86-88 °C(lit.)
storage temp.  2-8°C
solubility  DMF: 25 mg/ml
DMSO: 25 mg/ml
Ethanol: 10 mg/ml
PBS (pH 7.2): 3 mg/ml
form  Powder
color  White to off-white
PH 4.0 to 6.5(50g/L, 25 ℃)
Water Solubility  soluble
BRN  3594959
Stability: Stable for 2 years from date of purchase as supplied. Solutions are not stable and must be prepared fresh daily
InChIKey LZCZIHQBSCVGRD-UHFFFAOYSA-N

Description and Uses

Benzamidine hydrochloride is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases. A concentration of approximately 1 mM is used for general protease inhibition. To inhibit proteases from yeast, a range of 0.5 to 4.0 mM is used and it is for the most part interchangeable with pepstatin A.
In addition to being a strong competitive inhibitor of trypsin, benzamidine HCl has been also shown to be a strong competitive inhibitor of thrombin and plasmin. It was also found to be as effective as aprotinin in the prevention of glucagon degradation in human plasma.

Benzamidine is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Kis = 35, 350, and 220 μM, respectively). In addition to its use as a general serine protease inhibitor, benzamidine is used, when immobilized, to purify novel proteases.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-36
WGK Germany  3
RTECS  CV6260000
3-21
HS Code  29252900

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