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A1144750

CholesterolinMethanol , 200μg/mL,U=2.0%,k=2 , 57-88-5

Synonym(s):
Cholesterol;Cholesterol from wool fat;Cholesterol, Highly Purified - CAS 57-88-5 - Calbiochem;Cholesterolum;Synthetic cholesterol

CAS NO.:57-88-5

Empirical Formula: C27H46O

Molecular Weight: 386.66

MDL number: MFCD00003646

EINECS: 200-353-2

Pack Size Price Stock Quantity
5ml RMB151.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 148-150 °C
Boiling point: 360 °C
alpha  -36 º (c=2, dioxane)
Density  1.06
refractive index  1.5250 (estimate)
Flash point: 250 °C
storage temp.  -20°C
solubility  H2O: 0.002 mg/mL
form  powder
pka 15.03±0.70(Predicted)
Specific Gravity 1.067
color  white
Odor wh. or faintly yel. pearly granules or crystals, almost odorless
Water Solubility  negligible
Merck  14,2201
BRN  1915888
Dielectric constant 2.9(Ambient)
InChIKey HVYWMOMLDIMFJA-DPAQBDIFSA-N
LogP 9.619 (est)

Description and Uses

Cholesterol is a soft waxy substance that is a steroidal alcohol or sterol. It is the most abundant steroid in the human body and is a component of every cell. Cholesterol is essential to life and most animals and many plants contain this compound. Cholesterol biosynthesis occurs primarily in the liver, but it may be produced in other organs. A number of other substances are synthesized from cholesterol including vitamin D, steroid hormones (including the sex hormones), and bile salts. Cholesterol resides mainly in cell membranes.
Humans produce about 1 gram of cholesterol daily in the liver. Dietary cholesterol is consumed through food. High cholesterol foods are associated with saturated fats and trans-fatty acids (commonly called trans fats). Dietary cholesterol comes from animal products (plants contain minute amounts of cholesterol) such as meats and dairy products.

Cholesterol be used as pharmaceutical intermediates and be used as synthetic materials of liquid crystal polymers.

Safety

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H302-H315-H319-H331-H336-H351-H361d-H372
Precautionary statements  P201-P261-P304+P340+P312-P305+P351+P338-P308+P313-P403+P233
Hazard Codes  Xn,Xi
Risk Statements  10-48/20/22-40-38-22-36/37/38-67-36/38-20-63
Safety Statements  24/25-22-36/37-36-26
RIDADR  UN 1170 3/PG 3
WGK Germany  1
RTECS  FZ8400000
TSCA  Yes
HS Code  2906 13 10
HazardClass  IRRITANT
Toxicity Present in all parts of the animal body; concentrated in spinal cord, brain, skin secretions, and gallstones. An unsaturated, unsaponifiable alcohol (m.p. 149℃). It is synthesized in the body from ethanoate units; its metabolism is regulated by a specific set of enzymes. It is the parent compound of many other steroids and its presence in high concentrations in the blood is suspected as being a contributory factor in cardiovascular disease.

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