![(4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-7-Hydroxy-7-(2-hydroxyacetyl)-4a,6a,8-trimethyl-5a,6,6a,7,8,9,9a,9b,10,11-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2(4aH)-one](https://img.chemicalbook.com//CAS/GIF/981-34-0.gif)
A1142912
(4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-7-Hydroxy-7-(2-hydroxyacetyl)-4a,6a,8-trimethyl-5a,6,6a,7,8,9,9a,9b,10,11-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2(4aH)-one , 97% , 981-34-0
CAS NO.：981-34-0
Empirical Formula: C22H28O5
Molecular Weight: 372.45
MDL number: MFCD09038712
EINECS: 213-563-4
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB23.20 | In Stock |
|
| 250MG | RMB99.20 | In Stock |
|
| 1G | RMB248.80 | In Stock |
|
| 5g | RMB993.60 | In Stock |
|
| 25g | RMB3112.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 210-220 ºC |
| Boiling point: | 564.9±50.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| vapor pressure | 0-357.304Pa at 25℃ |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly, Heated), Dioxane (Slightly, Heated), DMSO (Slightly, Heated) |
| form | Solid |
| pka | 12.56±0.70(Predicted) |
| color | White to Light Beige |
| InChIKey | GBDXNHBVYAMODG-OBDZOPJXNA-N |
| SMILES | C[C@]12C=CC(=O)C=C1CC[C@@]1([H])[C@]3([H])C[C@H](C)[C@](O)(C(=O)CO)[C@@]3(C)C[C@@H]3O[C@]213 |&1:1,10,12,15,17,23,26,28,r| |
Description and Uses
9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione (Betamethasone EP Impurity E) is a metabolite of Mometasone Furoate (M490000) which is a tropical corticosteroid used as an anti-inflammatory. Low solubility in most solvent. 9,11β-epoxysteroid compounds can be prepared by 9-position fluorination to obtain dexamethasone. By modifying its 3-bit, 6-bit, 16-bit, and 21-bit, a series of drugs can be prepared.
9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione is a metabolite of Mometasone furoate. It has low solubility in most solvents.
