Cycloheximide , 95% , 66-81-9

Synonym(s):
CHX;Actidione;Cycloheximide - CAS 66-81-9 - Calbiochem;Cycloheximide, High Purity - CAS 66-81-9 - Calbiochem;InSolution Cycloheximide - CAS 66-81-9 - Calbiochem

CAS NO.：66-81-9

Empirical Formula: C15H23NO4

Molecular Weight: 281.35

MDL number: MFCD06202064

EINECS: 200-636-0

Update time: 2022-07-08

PRODUCT Properties

Melting point:	111-116 °C
alpha	-28.5 º (c=1, CHCl3)
Boiling point:	492℃
Density	1.0867 (rough estimate)
refractive index	1.5000 (estimate)
Flash point:	87°0°(230°F)
storage temp.	2-8°C
solubility	Soluble in Ethanol (up to 14 mg/ml) or in Water (up to 7 mg/ml).
form	Glassy Irregular Shaped Granules
pka	11.61±0.40(Predicted)
color	White
Water Solubility	2.1 g/100 mL (2 ºC)
BRN	88868
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, alkali.
CAS DataBase Reference	66-81-9(CAS DataBase Reference)
EPA Substance Registry System	Cycloheximide (66-81-9)

Description and Uses

Cycloheximide is a glutarimide-type antibiotic produced by Streptomyces griseus. Colorless crystals, C15H23NO4 (281.4), melting point: 115.5–117 ?C, weak acidic substance (pKa 11.2), Soluble in chloroform, isopropanol and methanol; water > 21 g/L (2 ?C). Stable in pH 3–5, but rapidly destroyed in alkaline solutions.

immunosuppressant

Safety

Symbol(GHS)	GHS06,GHS08
Signal word	Danger
Hazard statements	H301-H341-H360D-H412
Precautionary statements	P201-P202-P264-P270-P273-P301+P310
Hazard Codes	Xn,T,N,T+
Risk Statements	22-68-61-51/53-28-38-52/53
Safety Statements	53-45-61-36/37-28
RIDADR	UN 2811 6.1/PG 1
WGK Germany	3
RTECS	MA4375000
HazardClass	6.1(a)
PackingGroup	II
HS Code	29419000
Hazardous Substances Data	66-81-9(Hazardous Substances Data)
Toxicity	LD50 i.v. in mice: 150 mg/kg (Leach)