1,2-dimyristoyl-rac-glycero-3-methoxypolyethyleneglycol-2000 , ≥99% , 160743-62-4
Synonym(s):
1,2-Dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000
| Pack Size | Price | Stock | Quantity |
| 50mg | RMB399.20 | In Stock |
|
| 250mg | RMB1359.20 | In Stock |
|
| 1g | RMB3999.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| storage temp. | -20°C, sealed storage, away from moisture and light |
| solubility | DMSO: 100 mg/mL |
| form | A crystalline solid |
| color | White to light yellow |
Description and Uses
DMG-PEG 2000, also called 1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000, is used for liposome preparation. DMG-PEG 2000 has become known for lipid nanoparticle (LNP) preparation for siRNA (small interfering RNA) delivery in the COVID-19 vaccine development. DMG-PEG 2000 has been used in studies for anticancer drug delivery studies for hepatocellular, gastrointestinal, neuroendocrine and adrenocortical carcinoma.
DMG-PEG2000 is used for the preparation of liposomes for siRNA delivery, which can improve the transfection efficiency. It can also be used for the preparation of lipid nanoparticles for in vivo delivery of orally administered plasmid DNA. DMG-PEG2000 can improve the mucus permeability and delivery efficiency of nanoparticles.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
