Insulin(human) , BR , 11061-68-0

Synonym(s):
Bovine insulin;Insulin human;Insulin, Zinc, Human, Recombinant, P. pastoris;Cell culture grade insulin;Insulin from hog pancreas

CAS NO.：11061-68-0

Empirical Formula: C257H383N65O77S6

Molecular Weight:

MDL number: MFCD00131380

EINECS: 234-279-7

PRODUCT Properties

• Melting point: >200°C (dec.)
• storage temp.: -20°C
• solubility: acidified water, pH 2.0: 2 mg/mL
• form: solution
• color: White
• Water Solubility: Soluble up to 10mg/ml in pH <3 or in the presence of surfactants. Adjusting pH with a volatile acid (such as formic acid) prior to dry down will allow the product to be re-dissolved in water.

Description and Uses

Insulin (INS) is the only hormone lowering blood glucose levels in vertebrates. However, the importance of insulin in the carbohydrate metabolism may differ between mammals and other vertebrates. Frederick Banting and Charles Best discovered a substance that lowered blood sugar levels in the dog pancreas in 1921, and this was immediately applied to diabetes care. The primary structure of INS has been reported in many vertebrates, including agnathans, fish, and tetrapods.

Antidiabetic.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Safety Statements: 22-24/25
• WGK Germany: 3
• RTECS: NM8900250
• F: 3-10
• HS Code: 2937120000
• Toxicity: LD50 intraperitoneal in mouse: 3937units/kg