PRODUCT Properties
| Melting point: | 124-127 °C (lit.) |
| Boiling point: | 442.3±33.0 °C(Predicted) |
| Density | 1.238±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO, Methanol |
| pka | 14.80±0.10(Predicted) |
| form | Powder or Crystals |
| color | Red to brown |
| BRN | 4947 |
| InChIKey | PWSZRRFDVPMZGM-UHFFFAOYSA-N |
Description and Uses
3-Amino-5-phenylpyrazole ((3-phenyl-1H-pyrazol-5-amine) may be used in the synthesis of the following:
- Urea derivatives by reaction with azido(6-(benzofuran-2-yl)-2-methylpyridin-3-yl) methanone.
- 2-Mercaptoacetamide analogs by treating with thioglycolic acid.
- 3-(Substituentpyrimidayl)-5,6-benzocoumarins by treating with 3-(2′-formyl-1′-chlorovinyl)-5,6-benzocoumarin.
- Substituted 2,7-diphenylpyrazolo[1,5-a]pyrimidine-5-carboxylic esters by reacting with substituted β-diketo esters.
- N-ethoxycarbonylthiourea derivative by reacting with ethoxycarbonyl isothiocyanate.
- Heterobiaryl pyrazolo[3,4-b]pyridines by reacting with indole-3-carboxaldehyde.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280a-P304+P340-P405-P501a-P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 3 |
| RTECS | UQ6109000 |
| Hazard Note | Irritant |
| HS Code | 29331990 |
| Toxicity | mouse,LDLo,intraperitoneal,630mg/kg (630mg/kg),Farmakologiya i Toksikologiya Vol. 27, Pg. 295, 1964. |
