Acetyl chloride , 1MinDichloromethane , 75-36-5
Synonym(s):
Acetic acid chloride, Acetoxy chloride;Acetyl chloride
CAS NO.：75-36-5
Empirical Formula: C2H3ClO
Molecular Weight: 78.5
MDL number: MFCD00000719
EINECS: 200-865-6
PRODUCT Properties
| Melting point: | -112 °C |
| Boiling point: | 52 °C(lit.) |
| Density | 1.104 g/mL at 25 °C(lit.) |
| vapor density | 2.7 (vs air) |
| vapor pressure | 11.69 psi ( 20 °C) |
| refractive index | n |
| Flash point: | 40 °F |
| storage temp. | Store below +15°C. |
| solubility | Miscible with acetone, chloroform, glacial acetic acid, petroleum ether, ether and benzene. |
| form | Liquid |
| Specific Gravity | approximate 1.11 |
| color | Clear colorless |
| Odor | Strong pungent odor |
| explosive limit | 7.3-19%(V) |
| Water Solubility | Decomposes violently in water |
| Sensitive | Moisture Sensitive |
| Merck | 14,85 |
| BRN | 605303 |
| Dielectric constant | 16.9（2℃） |
| Stability: | Stability Highly flammable. Reacts violently with DMSO, water, lower alcohols, and amines to generate toxic fumes. May form an explosive mixture with air. Note low flash point. Incompatible with water, alcohols, amines, strong bases, strong oxidizing agents, most common metals. |
| InChIKey | WETWJCDKMRHUPV-UHFFFAOYSA-N |
| CAS DataBase Reference | 75-36-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetyl chloride(75-36-5) |
| EPA Substance Registry System | Acetyl chloride (75-36-5) |
Description and Uses
Acetic chloride is a colourless to light yellow liquid with a pungent and choking odour. Acetic chloride is highly flammable and reacts violently with DMSO, water, lower alcohols, and amines to generate toxic fumes. Along with air, acetic chloride may form an explosive mixture. It is incompatible with water, alcohols, amines, strong bases, strong oxidising agents, and most common metals. On decomposition when heated, acetic chloride produces carbon monoxide, carbon dioxide, hydrogen chloride, and phosgene.
Acetyl chloride acts as a reagent for the preparation of esters and amides of acetic acid. It is also useful an important reactant in Friedel-Crafts reactions as well as the introduction of an acetyl group. It serves as a starting material in the production of pharmaceutical, new plating complexing agent, acylation agent and synthetic organic intermediates.
Safety
| Symbol(GHS) |   GHS02,GHS05 |
| Signal word | Danger |
| Hazard statements | H225-H314 |
| Precautionary statements | P210-P233-P240-P280-P303+P361+P353-P305+P351+P338 |
| Hazard Codes | F,C,Xn |
| Risk Statements | 11-14-34-40-36/38 |
| Safety Statements | 9-16-26-45-1/2-36/37 |
| RIDADR | UN 1717 3/PG 2 |
| WGK Germany | 1 |
| RTECS | AO6390000 |
| F | 3 |
| Autoignition Temperature | 390 °C DIN 51794 |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | II |
| HS Code | 29159080 |
| Hazardous Substances Data | 75-36-5(Hazardous Substances Data) |
