Home Categories API 1-Adamantylamine
A0809012

1-Adamantylamine , ≥98.0%(GC) , 768-94-5

Synonym(s):
1-Aminoadamantane

CAS NO.:768-94-5

Empirical Formula: C10H17N

Molecular Weight: 151.25

MDL number: MFCD00074732

EINECS: 212-201-2

Pack Size Price Stock Quantity
1g RMB23.20 In Stock
5G RMB33.60 In Stock
25G RMB80.80 In Stock
100G RMB276.80 In Stock
500g RMB1215.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 206-208 °C(lit.)
Boiling point: 263.29°C (rough estimate)
Density  0.9510 (rough estimate)
refractive index  1.5220 (estimate)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  1 M HCl: soluble5%, clear to hazy, colorless to faint yellow or tan
form  Powder
pka 10.1(at 25℃)
color  White to cream
Water Solubility  Soluble in organic solvents. Insoluble in water.
Merck  14,374
BRN  2204333
InChIKey DKNWSYNQZKUICI-UHFFFAOYSA-N

Description and Uses

Amantadine is an agent that raises the concentration of dopamine in the synaptic cleft by releasing it from neurons and suppressing the process of reuptake.

Amantadine is a primary amine derivative of adamantane. It has an effect on mycoviruses, which are RNA-containing viruses. It has a very narrow spectrum of action and is used only for treating and preventing influenza A. It is also used for treating Parkinsonism. The exact mechanism of antiviral action of amantadine is not completely understood. It is believed that it is an ion channel blocker. It has also been suggested that amantadine inhibits absorption of viral particles into the host cell, which is expressed in the breakdown of diffusion of the virus into the cell, or inhibition of the “stripping process” of the virus. The main use is for the prevention of type A2 influenza. Synonyms of this drug are simmetrel, viregit, mantadan, and others.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P301+P312+P330-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  YD1925000
10-34
HS Code  29213000
Toxicity LD50 oral in rat: 900mg/kg

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