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A0801412

Alternariol , 96% , 641-38-3

Synonym(s):
3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one;3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one;3,7,9-Trihydroxy-1-methyl-benzo[c]chromen-6-one

CAS NO.:641-38-3

Empirical Formula: C14H10O5

Molecular Weight: 258.23

MDL number: MFCD00133068

Pack Size Price Stock Quantity
1MG RMB791.20 In Stock
5MG RMB3199.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 350°C (rough estimate)
Boiling point: 321.48°C (rough estimate)
Density  1.2211 (rough estimate)
refractive index  1.4560 (estimate)
storage temp.  2-8°C
solubility  ≤0.5mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
pka 7.16±0.20(Predicted)
form  Solid
color  Off-white to brown
BRN  244839
Stability: Hygroscopic

Description and Uses

Alternariol is a mycotoxin, a toxic secondary fungal metabolite, produced by Alternaria molds. It is cytotoxic, fetotoxic, teratogenic, mutagenic, and genotoxic. It induces cytochrome P450 1A1 expression and apoptosis in mouse hepatoma cells (20-40 μM). Alternariol, whose synthesis is inhibited by light, naturally occurs on fruits, vegetables, and cereals, such as apples, tomatoes, and wheat.

An alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing he rate of DNA strand breaks.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H300+H310+H330
Precautionary statements  P262-P280-P301+P310+P330-P302+P352+P310-P304+P340+P310
Hazard Codes  T+
Risk Statements  26/27/28
Safety Statements  28-36/37/39-45
RIDADR  UN 3462 6.1/PG 1
WGK Germany  3
RTECS  HP8757000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29322090
Toxicity LDLo intraperitoneal in mouse: 100mg/kg

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