A0788812
Acadesine , ≥98% , 2627-69-2
Synonym(s):
Acadesine;AMPK;PRKAB1;PRKAB2;PRKAG1
CAS NO.：2627-69-2
Empirical Formula: C9H14N4O5
Molecular Weight: 258.23
MDL number: MFCD00869751
EINECS: 220-097-5
| Pack Size | Price | Stock | Quantity |
| 50MG | RMB240.80 | In Stock |
|
| 250MG | RMB812.80 | In Stock |
|
| 1G | RMB2399.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 214-215 °C |
| Boiling point: | 726.3±60.0 °C(Predicted) |
| Density | 2.06±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | H2O: >10 mg/mL |
| form | powder |
| pka | 13.27±0.70(Predicted) |
| color | tan |
| Water Solubility | Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at less than 1mg/ml |
| λmax | 265nm(NaOH)(lit.) |
| Merck | 14,16 |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months. |
| InChIKey | RTRQQBHATOEIAF-UUOKFMHZSA-N |
| CAS DataBase Reference | 2627-69-2(CAS DataBase Reference) |
| EPA Substance Registry System | 1H-Imidazole-4-carboxamide, 5-amino-1-.beta.-D-ribofuranosyl- (2627-69-2) |
Description and Uses
AICAR (2627-69-2) activates AMP-activated protein kinase (AMPK). Promotes ligand-independent activation of the insulin receptor.1 Promotes skeletal muscle autophagy via activation of FoxO3a.2 Controls smooth muscle cell hyperproliferation in vascular disease.3 ?Induces osteogenic differentiation in mesenchymal stem cells.4 Inhibits proinflammatory response in glial cells.5 Cell permeable.
glucose uptake stimulant; AMPK activator
Safety
| Symbol(GHS) |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315-H319-H360D |
| Precautionary statements | P202-P264-P280-P302+P352-P305+P351+P338-P308+P313 |
| Hazard Codes | Xi,T |
| Risk Statements | 36/37/38-61 |
| Safety Statements | 26-36-45-53 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29349990 |
