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A0788712

Avasimibe , ≥98% , 166518-60-1

Synonym(s):
CI-1011; PD 148515; [[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl ester] sulfamic acid

CAS NO.:166518-60-1

Empirical Formula: C29H43NO4S

Molecular Weight: 501.72

MDL number: MFCD00934956

EINECS: 1592732-453-0

Pack Size Price Stock Quantity
10MG RMB399.20 In Stock
50MG RMB1439.20 In Stock
250MG RMB4799.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 178-180° (Lee); mp 169.5-170.4° (Dozeman)
Density  1.072±0.06 g/cm3(Predicted)
storage temp.  room temp
solubility  DMSO: ≥40mg/mL
form  powder
pka 1.97±0.70(Predicted)
color  white to tan
InChIKey PTQXTEKSNBVPQJ-UHFFFAOYSA-N

Description and Uses

Avasimibe has been used as an inhibitor of acyl-coenzyme A: cholesterol acyltransferase (ACAT) in Huh7.5.1 cells for testing its combination with direct-acting antivirals (DAAs) and to test its effect on lipid droplet accumulation in acidosis-adapted cancer cells. It may be used as an inhibitor of ACAT to assess cholesterol esterification in Trypanosoma cruzi.

Safety

WGK Germany  3
HS Code  2935909099

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