Home Categories API Azelastine HCl
A0784112

Azelastine HCl , ≥98%(HPLC) , 79307-93-0

Synonym(s):
4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one hydrochloride;Astelin;Azelastine hydrochloride;Optivar

CAS NO.:79307-93-0

Empirical Formula: C22H25Cl2N3O

Molecular Weight: 418.36

MDL number: MFCD00242783

EINECS: 620-469-0

Pack Size Price Stock Quantity
100MG RMB63.20 In Stock
250MG RMB119.20 In Stock
1G RMB234.40 In Stock
5G RMB778.40 In Stock
25G RMB2270.40 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 225--2290C
storage temp.  Inert atmosphere,Store in freezer, under -20°C
solubility  DMSO: >10mg/mL
form  powder
color  white to off-white
Merck  14,906
Stability: Incompatible with strong oxidizing agents.
InChI InChI=1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H
InChIKey YEJAJYAHJQIWNU-UHFFFAOYSA-N
SMILES C1(=O)C2=C(C=CC=C2)C(CC2=CC=C(Cl)C=C2)=NN1C1CCCN(C)CC1.[H]Cl
CAS DataBase Reference 79307-93-0(CAS DataBase Reference)

Description and Uses

Azelastine hydrochloride is an orally effective antihistamine useful in the treatment of asthma and nasal allergy. It appears to inhibit release of histamine, in addition to antagonizing its action.

Orally active H1-hystamine receptor antagonist. Antihistaminic

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22
RTECS  TH9203900
HS Code  2933992600
Toxicity LD50 in male, female mice, male, female rats (mg/kg): 36.5, 35.5, 26.9, 30.3 i.v.; 56.4, 42.8, 43.2, 46.6 i.p.; 63.0, 54.2, 66.5, 59.6 s.c.; 124, 139, 310, 417 orally (Zechel)

RELATED PRODUCTS