O-Acetyl-L-carnitine hydrochloride , 99% , 5080-50-2

Synonym(s):
(R)-3-Acetoxy-4-(trimethylammonio)butyrate hydrochloride;Acetyl L-carnitine HCl;ALC;ALCAR;R-(−)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride

CAS NO.：5080-50-2

Empirical Formula: C9H18ClNO4

Molecular Weight: 239.7

MDL number: MFCD00082230

EINECS: 1308068-626-2

PRODUCT Properties

• Melting point: 194 °C (dec.)(lit.)
• alpha: -29 º (c=1, H2O)
• refractive index: -28 ° (C=1, H2O)
• storage temp.: 2-8°C
• solubility: H₂O: 100 mg/mL
• form: powder
• color: white
• optical activity: [α]25/D 28°, c = 2 in H2O(lit.)
• Water Solubility: soluble
• Sensitive: Hygroscopic
• Merck: 14,84
• BRN: 4340103
• InChI: InChI=1/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/s3
• InChIKey: JATPLOXBFFRHDN-DDWIOCJRSA-N
• SMILES: C([N+](C)(C)C)[C@H](OC(=O)C)CC(=O)O.[Cl-] |&1:5,r|
• LogP: -4.149 (est)

Description and Uses

Levacecarnine hydrochloride is a nootropic agent structurally related to the natural substance L-carnitine. It is reported to be useful in the treatment of cognition disorders in the elderly, perhaps due to its weak cholinergic properties.

O-Acetyl-L-carnitine hydrochloride is used as a cholinergic agonist that stimulates neuronal response to serotonin and acetylcholine. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• F: 3-9
• HS Code: 29239000