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A0772412

AN-2690 , ≥98.0% , 174671-46-6

Synonym(s):
1,3-Dihydro-5-fluoro-1-hydroxy-2,1-benzoxaborole;5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole;AN2690;AN-2690

CAS NO.:174671-46-6

Empirical Formula: C7H6BFO2

Molecular Weight: 151.93

MDL number: MFCD10699483

Pack Size Price Stock Quantity
5MG RMB39.20 In Stock
10MG RMB47.20 In Stock
50MG RMB55.20 In Stock
100MG RMB64.00 In Stock
250mg RMB89.60 In Stock
1g RMB230.40 In Stock
5g RMB1023.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 120-122℃
Boiling point: 230.8±50.0 °C(Predicted)
Density  1.28±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  DMSO (Slightly), Methanol (Slightly)
pka 6.81±0.20(Predicted)
form  powder
color  white to beige
Stability: Hygroscopic

Description and Uses

Tavaborole (Kerydin®), discovered and developed by Anacor, was approved by the US FDA in July 2014. Tavaborole, topical solution, 5% is an oxaborole antifungal indicated for the treatment of onychomycosis of the toenails due to Trichophyton rubrum or Trichophyton mentagrophytes. The mechanism of action of tavaborole is inhibition of fungal protein synthesis, which inhibits an aminoacyl-transfer ribonucleic acid synthetase.

Tavaborole is a topical treatment of toenail onychomycosis.

Safety

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