Home Categories Organic Chemistry 2-Amino-6-fluorobenzonitrile
A0754412

2-Amino-6-fluorobenzonitrile , 99% , 77326-36-4

Synonym(s):
6-Fluoroanthranilonitrile

CAS NO.:77326-36-4

Empirical Formula: C7H5FN2

Molecular Weight: 136.13

MDL number: MFCD00015477

Pack Size Price Stock Quantity
1G RMB23.20 In Stock
5G RMB24.00 In Stock
25G RMB64.80 In Stock
100G RMB235.20 In Stock
500g RMB959.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 125-128 °C (lit.)
Boiling point: 275.8±25.0 °C(Predicted)
Density  1.25±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Chloroform
form  Solid
pka 0.80±0.10(Predicted)
color  Pale Yellow
BRN  3588945
CAS DataBase Reference 77326-36-4(CAS DataBase Reference)

Description and Uses

2-Amino-6-fluorobenzonitrile, a medicinal chemistry intermediate, has been employed for the preparation of tacrine-related compounds. It may be used for the synthesis of antifolate and antibacterial quinazoline derivatives.
It may be used for the synthesis bis(4-oxoquinazolin-2-yl)pyridine and fluoro-containing quinazolin-4(1H)-ones. It may be employed for the synthesis of the following novel huprines:

  • 12-amino-3-chloro-6,7,10,11-tetrahydro-9-isopropyl-7,11-methanocycloocta[b]quinoline hydrochloride
  • 9-allyl-12-amino-3-chloro-6,7,10,11-tetrahydro-7,11-methanocycloocta[b]quinoline hydrochloride
  • 12-amino-1-fluoro-6,7,10,11-tetrahydro-9-isopropyl-7,11-methanocycloocta[b]quinoline hydrochloride
  • 9-allyl-12-amino-1-fluoro-6,7,10,11-tetrahydro-7,11-methanocycloocta[b]quinoline hydrochloride

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi,T,Xn
Risk Statements  36-36/37/38-20/21/22
Safety Statements  26-36-36/37/39-22
RIDADR  3439
WGK Germany  2
Hazard Note  Irritant
HazardClass  6.1
PackingGroup  III
HS Code  29269090

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