4-Amino-3-methylphenol , 98% , 2835-99-6

Synonym(s):
2-Amino-5-hydroxytoluene;4-Amino-m-cresol;4-Hydroxy-2-methylaniline

CAS NO.：2835-99-6

Empirical Formula: C7H9NO

Molecular Weight: 123.15

MDL number: MFCD00007871

EINECS: 220-621-2

PRODUCT Properties

• Melting point: 176-179 °C (lit.)
• Boiling point: 229.26°C (rough estimate)
• Density: 1.0877 (rough estimate)
• refractive index: 1.5380 (estimate)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: soluble in Methanol
• pka: 10.34±0.18(Predicted)
• form: Powder
• color: Brown
• Water Solubility: insoluble
• BRN: 2078803
• InChIKey: QGNGOGOOPUYKMC-UHFFFAOYSA-N
• LogP: 0.51 at 22℃
• CAS DataBase Reference: 2835-99-6(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-3-methyl phenol(2835-99-6)
• EPA Substance Registry System: Phenol, 4-amino-3-methyl- (2835-99-6)

Description and Uses

4-Amino-3-methylphenol is a metabolite of 3-methyl-4-nitrophenol. It is a major metabolite of carcinogenic o-toluidine and causes DNA damage in the presence of Cu(II).

4-Amino-3-methylphenol is a useful reagent for the synthesis of piperidine (piperazine)-amide substituted derivatives as multi-target antipsychotics.
4-Amino-3-methylphenol was used in synthesis of a new type of tweezer-molecule in which a strongly preferred binding conformation is generated by convergent, intramolecular hydrogen bonding.

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H302-H315-H319-H400
• Precautionary statements: P273-P301+P312+P330-P302+P352-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 22-36/37/38-20/21/22
• Safety Statements: 26-37/39-36/37/39-36-24/25
• RIDADR: UN3077
• WGK Germany: 3
• RTECS: GO6826000
• F: 8-10-23
• TSCA: Yes
• HazardClass: 9
• PackingGroup: III
• HS Code: 29222900