Home Categories 2-Amino-4-phenylthiazole
A0704112

2-Amino-4-phenylthiazole , 98% , 2010-06-2

CAS NO.:2010-06-2

Empirical Formula: C9H8N2S

Molecular Weight: 176.24

MDL number: MFCD00039680

EINECS: 217-926-8

Pack Size Price Stock Quantity
1G RMB77.60 In Stock
5G RMB783.20 In Stock
25g RMB1519.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 149-153 °C (lit.)
Boiling point: 363.4±11.0 °C(Predicted)
Density  1.261±0.06 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml
pka 4.33±0.10(Predicted)
form  Crystalline Solid
color  White to yellow to pale orange
λmax 284nm(EtOH)(lit.)
BRN  128609
InChIKey PYSJLPAOBIGQPK-UHFFFAOYSA-N
CAS DataBase Reference 2010-06-2(CAS DataBase Reference)
NIST Chemistry Reference 2-Thiazolamine, 4-phenyl-(2010-06-2)

Description and Uses

2-amino-4-phenyl Thiazole is a synthetic intermediate useful for pharmaceutical synthesis.

4-Phenyl-2-thiazolamine was used to prepare suberoylanilide hydroxamic acid (SAHA) analogs with cancer cell growth inhibitory activities. It was also used to synthesize ketone histone deacetylase inhibitors with antitumor activity in vivo.

Safety

Symbol(GHS) 
GHS05,GHS06,GHS07
Signal word  Danger
Hazard statements  H319-H301-H315-H318-H335
Precautionary statements  P301+P310a-P321-P501a-P264-P270-P301+P310+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P405-P501-P261-P280-P301+P310-P305+P351+P338
Hazard Codes  Xn,Xi,T
Risk Statements  22-37/38-41-25
Safety Statements  26-36/37/39-45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
RTECS  XJ2878000
HazardClass  6.1
HazardClass  IRRITANT
PackingGroup  III
HS Code  29341000
Toxicity mouse,LD50,intravenous,320mg/kg (320mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00815,

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