Home Categories Pharmaceutical intermediates 2-Amino-4,6-dichloropyrimidine
A0703512

2-Amino-4,6-dichloropyrimidine , 98% , 56-05-3

CAS NO.:56-05-3

Empirical Formula: C4H3Cl2N3

Molecular Weight: 163.99

MDL number: MFCD00006090

EINECS: 200-253-9

Pack Size Price Stock Quantity
5G RMB29.60 In Stock
25G RMB36.00 In Stock
100G RMB83.20 In Stock
500G RMB388.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 219-222 °C (lit.)
Boiling point: 219-222°C
Density  1.6662 (rough estimate)
refractive index  1.6300 (estimate)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
pka 0.14±0.10(Predicted)
form  Liquid
color  Clear colorless to light yellow
Water Solubility  Insoluble in water, soluble in acetone, two monomer (VCM) and thermal toluene.
BRN  118454
InChIKey JPZOAVGMSDSWSW-UHFFFAOYSA-N
CAS DataBase Reference 56-05-3(CAS DataBase Reference)
EPA Substance Registry System 2-Pyrimidinamine, 4,6-dichloro- (56-05-3)

Description and Uses

Microwave-assisted synthesis of pyrazolo [3, 4-d] pyrimidines from 2-amino-4, 6-dichloropyrimidine-5-carbaldehyde is under solvent-free conditions. A series of 6-alkynyl-2,4-diaminopyrimidine derivatives bearing various substituents at alkynyl moiety was prepared by the Sonogashira cross-coupling reaction of 2,4-diamino-6-iodopyrimidine using Pd(PPh3)2Cl2 as catalyst.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
WGK Germany  3
RTECS  UV6260485
10
TSCA  T
HazardClass  IRRITANT
HS Code  29335995

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