Ammothamnine , Analysis standard , 16837-52-8

CAS NO.：16837-52-8

Empirical Formula: C15H24N2O2

Molecular Weight: 264.36

MDL number: MFCD00210339

EINECS: 605-514-4

PRODUCT Properties

• Melting point: 208℃
• storage temp.: Inert atmosphere,2-8°C
• solubility: methanol: soluble10mg/mL, clear, colorless
• pka: 4.87±0.20(Predicted)
• form: powder
• color: white to off-white
• Stability: Hygroscopic
• InChIKey: XVPBINOPNYFXID-LHDUFFHYSA-N

Description and Uses

Oxymatrine is a natural alkaloid isolated from the root of S. flavescens, an herb used in traditional Chinese herbal medicine. It has antiviral properties, inhibiting the replication of hepatitis B alone and in combination with lamivudine. Oxymatrine also prevents fibrosis in a number of organs including liver, at least in part by interfering with TGF-β signaling. This compound also induces apoptosis in certain cancer cells and ameliorates inflammation by impairing the translocation of nuclear factors-κB.

Oxymatrine is a an anti-tumor agent triggering apoptosis in human leukemia cells.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264b-P270-P301+P312-P330-P403-P501c
• Hazard Codes: Xn
• Risk Statements: 22-20/22
• Safety Statements: 24/25
• WGK Germany: 3
• RTECS: OQ1770000
• HS Code: 29399990