DiallylTrisulfide , 65% , 2050-87-5
Synonym(s):
Allyl trisulfide;Di-2-propenyl trisulfide
CAS NO.：2050-87-5
Empirical Formula: C6H10S3
Molecular Weight: 178.34
MDL number: MFCD00040025
EINECS: 218-107-8
| Pack Size | Price | Stock | Quantity |
| 5g | RMB181.60 | In Stock |
|
| 25g | RMB495.20 | In Stock |
|
| 100g | RMB1263.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | bp6 92°; bp0.0008 66-67° |
| Density | 1.085 |
| FEMA | 3265 | DIALLYL TRISULFIDE |
| refractive index | nD20 1.5896 |
| storage temp. | -20°C |
| solubility | Soluble in acetone, Ethanol(~3 mg/ml), DMSO (~5 mg/ml), and DMF (~10 mg/ml). |
| form | oil |
| color | Colorless to light yellow |
| Odor | at 0.10 % in propylene glycol. garlic green onion metallic |
| Odor Type | sulfurous |
| Water Solubility | insoluble in water. |
| JECFA Number | 587 |
| InChI | InChI=1S/C6H10S3/c1-3-5-7-9-8-6-4-2/h3-4H,1-2,5-6H2 |
| InChIKey | UBAXRAHSPKWNCX-UHFFFAOYSA-N |
| SMILES | S(SCC=C)SCC=C |
| LogP | 4.59 |
| CAS DataBase Reference | 2050-87-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Trisulfide, di-2-propenyl(2050-87-5) |
Description and Uses
Hydrogen sulfide (H2S) is an endogenously-produced gaseous second messenger that can regulate many physiological processes. Diallyl trisulfide (DATS) is an organic polysulfide compound found in garlic that acts as an H2S donor. It reduces the survival of prostate cancer PC-3 cells (IC50 = 22 μM) and inhibits the growth of human colon adenocarcinoma HCT15 cells (IC50 = 11.5 μM). DATS suppresses the growth of PC-3 xenografts in vivo in mice and induces vascular smooth muscle relaxation. Garlic extracts also lower cholesterol and there is evidence that DATS can alter the expression of genes and inhibit enzymes that are relevant to cholesterol synthesis.
Diallyl trisulfide (DATS) has been used to study its antimicrobial effects against Campylobacter jejuni. It has also been used to test its effect on hepatic regeneration in partial hepatectomy (PHx) rats.
