Home Categories Organic Chemistry Acetyl chloride
A0659412

Acetyl chloride , 99%, colorless , 75-36-5

Synonym(s):
Acetic acid chloride, Acetoxy chloride;Acetyl chloride

CAS NO.:75-36-5

Empirical Formula: C2H3ClO

Molecular Weight: 78.5

MDL number: MFCD00000719

EINECS: 200-865-6

Update time: 2022-07-08

PRODUCT Properties

Melting point: -112 °C
Boiling point: 52 °C(lit.)
Density  1.104 g/mL at 25 °C(lit.)
vapor density  2.7 (vs air)
vapor pressure  11.69 psi ( 20 °C)
refractive index  n20/D 1.389(lit.)
Flash point: 40 °F
storage temp.  Store below +15°C.
solubility  Miscible with acetone, chloroform, glacial acetic acid, petroleum ether, ether and benzene.
form  Liquid
color  Clear colorless
Specific Gravity approximate 1.11
Odor Strong pungent odor
explosive limit 7.3-19%(V)
Water Solubility  Decomposes violently in water
Sensitive  Moisture Sensitive
Merck  14,85
BRN  605303
Dielectric constant 16.9(2℃)
Stability: Stability Highly flammable. Reacts violently with DMSO, water, lower alcohols, and amines to generate toxic fumes. May form an explosive mixture with air. Note low flash point. Incompatible with water, alcohols, amines, strong bases, strong oxidizing agents, most common metals.
InChIKey WETWJCDKMRHUPV-UHFFFAOYSA-N

Description and Uses

Acetic chloride is a colourless to light yellow liquid with a pungent and choking odour. Acetic chloride is highly flammable and reacts violently with DMSO, water, lower alcohols, and amines to generate toxic fumes. Along with air, acetic chloride may form an explosive mixture. It is incompatible with water, alcohols, amines, strong bases, strong oxidising agents, and most common metals. On decomposition when heated, acetic chloride produces carbon monoxide, carbon dioxide, hydrogen chloride, and phosgene.

Acetyl chloride acts as a reagent for the preparation of esters and amides of acetic acid. It is also useful an important reactant in Friedel-Crafts reactions as well as the introduction of an acetyl group. It serves as a starting material in the production of pharmaceutical, new plating complexing agent, acylation agent and synthetic organic intermediates.

Safety

Symbol(GHS) 
GHS02,GHS05
Signal word  Danger
Hazard statements  H225-H314
Precautionary statements  P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
Hazard Codes  F,C,Xn
Risk Statements  11-14-34-40-36/38
Safety Statements  9-16-26-45-1/2-36/37
RIDADR  UN 1717 3/PG 2
WGK Germany  1
RTECS  AO6390000
3
Autoignition Temperature 390 °C DIN 51794
TSCA  Yes
HazardClass  3
PackingGroup  II
HS Code  29159080

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