m-Anisidine , 98% , 536-90-3
Synonym(s):
3-Aminoanisole;3-Methoxyaniline
CAS NO.：536-90-3
Empirical Formula: C7H9NO
Molecular Weight: 123.15
MDL number: MFCD00007783
EINECS: 208-651-4
PRODUCT Properties
| Melting point: | −1-1 °C(lit.) |
| Boiling point: | 251 °C(lit.) |
| Density | 1.096 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| solubility | 18g/l |
| pka | 4.23(at 25℃) |
| form | Liquid |
| color | Clear yellow to brown |
| Water Solubility | <0.1 g/100 mL at 19 ºC |
| Sensitive | Light Sensitive |
| Merck | 14,667 |
| BRN | 386119 |
| InChIKey | NCBZRJODKRCREW-UHFFFAOYSA-N |
| LogP | 0.930 |
| CAS DataBase Reference | 536-90-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzenamine, 3-methoxy-(536-90-3) |
| EPA Substance Registry System | m-Anisidine (536-90-3) |
Description and Uses
Anisidine exists as ortho-, meta-, and paraisomers. They have characteristic amine (fishy) odors.o-isomer: A colorless to pink liquid. Solid below 5℃.Molecular weight= 123.17; Boiling point= 224℃;Melting/Freezing point= 5℃; Vapor pressure=,0.1 mmHg at 20℃; Flash point= 118℃ (oc);Autoignition temperature= 415℃. Hazard Identification(based on NFPA-704 M Rating System): Health 2,Flammability 1, Reactivity 0. Practically insoluble in water;solubility=1.5%.m-isomer: Pale yellow liquid. Molecular weight= 123.2;Boiling point= 251℃; Freezing/Melting point= 57.2℃;Vapor pressure= 0.006 mmHg at 20℃.p-isomer: Reddish-brown solid. Molecular weight= 123.2;Boiling point= 243℃; Freezing/Melting point= 57.2℃;Vapor pressure: 0.4 mmHg at 20℃; Flash point= 122℃;Autoignition temperature= 515℃. Hazard Identification(based on NFPA-704 M Rating System): Health 2,Flammability 0, Reactivity 0. Insoluble in water.
The unusually large amount of dibromo product produced upon bromination of m-anisidine may be attributed to the two doubly activeated positions. The best enantioselectivity of 97 % ee was observed for the reaction of m-anisidine in organocatalytic asymmetric three-component cyclization of cinnamaldehydes and primary amines with 1, 3-Dicarbonyl Compounds. Evidence for the control of 2nd-harmonic generation activities from the x-ray crystal-structures of the complexes of l-tartaric acid with m-anisidine and p-toluidine was determined.
Safety
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H301+H311+H331-H373-H410 |
| Precautionary statements | P273-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311-P314 |
| Hazard Codes | Xn,N,T+ |
| Risk Statements | 22-36/37/38-50/53-51/53-33-26/27/28 |
| Safety Statements | 26-60-61-45-36/37-28B |
| RIDADR | UN 2431 6.1/PG 3 |
| WGK Germany | 1 |
| RTECS | BZ5408000 |
| F | 8 |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29222200 |
| Hazardous Substances Data | 536-90-3(Hazardous Substances Data) |
| Toxicity | cyt-ham:ovr 160 mg/L EMMUEG 10(Suppl 10),1,87 |
