5-Aminolevulinic acid hydrochloride , 99% , 5451-09-2

Synonym(s):
ALA;5-Aminolevulinic acid hydrochloride;5-Amino-4-oxopentanoic acid hydrochloride;5-Aminolaevulinic acid hydrochloride;δ-Aminolevulinic acid hydrochloride

CAS NO.：5451-09-2

Empirical Formula: C5H10ClNO3

Molecular Weight: 167.59

MDL number: MFCD00012869

EINECS: 226-679-5

PRODUCT Properties

• Melting point: ~150 °C (dec.)
• Flash point: 155-157°C
• storage temp.: -20°C
• solubility: H₂O: 50 mg/mL
• form: powder
• color: White to pale yellow
• PH: pH (10g/l, 25℃) : 2.5～3.0
• Water Solubility: Soluble in dimethyl sulfoxide, methanol and water.
• Sensitive: Hygroscopic
• Decomposition: 155-157 ºC
• Merck: 14,446
• BRN: 3690651
• Stability: Hygroscopic
• InChIKey: ZLHFONARZHCSET-UHFFFAOYSA-N

Description and Uses

5-Aminolevulinic acid hydrochloride (5-ALA) is a naturally occurring amino acid that is an intermediate in the biosynthesis of chlorophyll and haemoglobin. It has anti-inflammatory, antioxidant and antitumour activities, and 5-Aminolevulinic acid hydrochloride-mediated sonodynamic therapy (SDT) has antitumour effects on pancreatic cancer cells. In addition, it is a visualising agent that causes high-grade gliomas to fluoresce under blue light, which can help guide surgeons in removing tumours and is considered a useful imaging tool for brain tumour resection.

5-Aminolevulinic acid hydrochloride has been used as a supplement for culturing Escherichia coli cells for heme biosynthesis.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-66-20/21/22-36/38
• Safety Statements: 26-36/37-37/39-36
• WGK Germany: 3
• RTECS: OI1640000
• F: 3-8-10
• Hazard Note: Irritant
• HS Code: 29224999