Home Categories Biochemical Engineering N-Acetyl-L-Cysteine
A0636312

N-Acetyl-L-Cysteine , USP,EP,≥98.5% , 616-91-1

Synonym(s):
N-Acetyl-L-cysteine;NAC;ACAC;2-Acetamido-3-mercaptopropionic acid;ACACA

CAS NO.:616-91-1

Empirical Formula: C5H9NO3S

Molecular Weight: 163.19

MDL number: MFCD00004880

EINECS: 210-498-3

Pack Size Price Stock Quantity
250g RMB215.20 In Stock
1KG RMB719.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 106-108 °C(lit.)
Boiling point: 407.7±40.0 °C(Predicted)
alpha  -35.1 ºC (c=2,H2O)
Density  1.249 (estimate)
vapor pressure  0Pa at 20℃
refractive index  24 ° (C=JPC Method)
storage temp.  2-8°C
solubility  H2O: 100 mg/mL with heating
pka pK1: 9.52 (30°C)
form  Solid
color  White
Water Solubility  Soluble in water, ethanol, methanol, dimethyl sulfoxide, hot isopropyl alcohol, methyl acetate and ethyl acetate. Insoluble in chloroform and ether.
Merck  14,88
BRN  1724426
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey PWKSKIMOESPYIA-BYPYZUCNSA-N
LogP -0.6 at 23℃

Description and Uses

N-Acetyl-L-cysteine is an N-acetylated derivative of cysteine, which contains a sulfhydryl group in the molecule, which can break the disulfide bond (-S-S-) of the mucin peptide bond, so that the mucin chain becomes a small molecule peptide chain, reducing The viscosity of mucin, so It is a dissolving drug for mucus in mucus, purulent sputum and respiratory tract.

A metabolite of Methyl Isocyanate.
N-Acetyl-L-cysteine, by itself a poor scavenger of oxidants, is converted inside cells to yield sulfane sulfur species, which are very potent scavengers of oxidants.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313
Risk Statements  36/37/38
Safety Statements  22-24/25
WGK Germany  3
RTECS  HA1660000
10-23
TSCA  Yes
HS Code  29309016
Toxicity LD50 orally in rats: 5050 mg/kg (Goldenthal)

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