11-Aminoundecanoic acid , 97% , 2432-99-7
Synonym(s):
11-Aminoundecanoic acid
CAS NO.：2432-99-7
Empirical Formula: C11H23NO2
Molecular Weight: 201.31
MDL number: MFCD00008150
EINECS: 219-417-6
| Pack Size | Price | Stock | Quantity |
| 25G | RMB111.20 | In Stock |
|
| 100G | RMB294.40 | In Stock |
|
| 250G | RMB639.20 | In Stock |
|
| 500G | RMB1039.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 188-191 °C (lit.) |
| Boiling point: | 339.24°C (rough estimate) |
| Density | 0.9896 (rough estimate) |
| refractive index | 1.4420 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | 2g/l |
| form | Crystalline Powder |
| pka | 4.78±0.10(Predicted) |
| color | White |
| Water Solubility | 2 g/L (20 ºC) |
| BRN | 1767291 |
| InChIKey | GUOSQNAUYHMCRU-UHFFFAOYSA-N |
| LogP | -0.16 at 20℃ |
Description and Uses
Aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. Aminoundecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
11-Aminoundecanoic Acid is used to prepare thapsigargin analogues targeting apoptosis to prostatic cancer cells. It is also used to synthesize N-carboxyalkylpeptides containing extended alkyl residues at P1''as matrix metalloproteinase inhibitors.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Risk Statements | 52 |
| Safety Statements | 24/25 |
| WGK Germany | 1 |
| RTECS | YQ2293000 |
| HS Code | 29224995 |
| Toxicity | LDLo orl-rat: 14,700 mg/kg NTPTR* NTP-TR-216,82 |
