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A0628712

ALuminon , ACS , 569-58-4

Synonym(s):
ATA;Aluminon;Aurintricarboxylic acid ammonium salt;Aurin tricarboxylic acid ammonium salt;Aluminon, Ammonium aurin tricarboxylate

CAS NO.:569-58-4

Empirical Formula: C22H17NO9

Molecular Weight: 439.38

MDL number: MFCD00040925

EINECS: 209-319-1

Pack Size Price Stock Quantity
25G RMB159.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 220-225 °C (dec.)(lit.)
Boiling point: 573.92°C (rough estimate)
Density  1.4414 (rough estimate)
refractive index  1.6300 (estimate)
storage temp.  room temp
solubility  DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 100 μg/ml
Colour Index  43810
form  powder
color  Deep red
PH 5.3 (10g/l, H2O, 20°C)
Water Solubility  800 g/L (20 ºC)
Merck  14,322
BRN  3900820
Stability: Stable.
CAS DataBase Reference 569-58-4
EPA Substance Registry System Benzoic acid, 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methyl]-2-hydroxy-, triammonium salt (569-58-4)

Description and Uses

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P280a-P305+P351+P338-P321-P332+P313-P337+P313-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
Risk Statements  36/38-36/37/38
Safety Statements  26-36-37/39
WGK Germany  2
RTECS  GU4800000
TSCA  Yes
HS Code  29189090
Toxicity LD50 orally in Rabbit: 9000 mg/kg

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