A0628712
ALuminon , ACS , 569-58-4
Synonym(s):
ATA;Aluminon;Aurintricarboxylic acid ammonium salt;Aurin tricarboxylic acid ammonium salt;Aluminon, Ammonium aurin tricarboxylate
CAS NO.：569-58-4
Empirical Formula: C22H17NO9
Molecular Weight: 439.38
MDL number: MFCD00040925
EINECS: 209-319-1
| Pack Size | Price | Stock | Quantity |
| 25G | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 220-225 °C (dec.)(lit.) |
| Boiling point: | 573.92°C (rough estimate) |
| Density | 1.4414 (rough estimate) |
| refractive index | 1.6300 (estimate) |
| storage temp. | room temp |
| solubility | DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 100 μg/ml |
| Colour Index | 43810 |
| form | powder |
| color | Deep red |
| PH | 5.3 (10g/l, H2O, 20°C) |
| Water Solubility | 800 g/L (20 ºC) |
| Merck | 14,322 |
| BRN | 3900820 |
| Stability: | Stable. |
Description and Uses
It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P280a-P305+P351+P338-P321-P332+P313-P337+P313-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 |
| Hazard Codes | Xi |
| Risk Statements | 36/38-36/37/38 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 2 |
| RTECS | GU4800000 |
| TSCA | Yes |
| HS Code | 29189090 |
| Toxicity | LD50 orally in Rabbit: 9000 mg/kg |
