Anisole , AR,99% , 100-66-3
Synonym(s):
Anisole;Methoxybenzene;Methyl phenyl ether;Methyl phenyl ether, Methoxybenzene
CAS NO.：100-66-3
Empirical Formula: C7H8O
Molecular Weight: 108.14
MDL number: MFCD00008354
EINECS: 202-876-1
PRODUCT Properties
| Melting point: | -37 °C (lit.) |
| Boiling point: | 154 °C (lit.) |
| Density | 0.995 g/mL at 25 °C (lit.) |
| vapor density | 3.7 (vs air) |
| vapor pressure | 10 mm Hg ( 42.2 °C) |
| refractive index | n |
| FEMA | 2097 | ANISOLE |
| Flash point: | 125 °F |
| storage temp. | Store below +30°C. |
| solubility | 1.71g/l |
| form | Liquid |
| color | Clear colorless |
| Relative polarity | 0.198 |
| Odor | phenol, anise odor |
| Odor Type | phenolic |
| explosive limit | 0.34-6.3%(V) |
| Odor Threshold | 0.057ppm |
| Water Solubility | 1.6 g/L (20 ºC) |
| Merck | 14,669 |
| JECFA Number | 1241 |
| BRN | 506892 |
| Dielectric constant | 4.3（20℃） |
| Stability: | Stable. Flammable. Incompatible with strong oxidizing agents. |
| InChIKey | RDOXTESZEPMUJZ-UHFFFAOYSA-N |
| LogP | 2.62 at 30℃ |
| CAS DataBase Reference | 100-66-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, methoxy-(100-66-3) |
| EPA Substance Registry System | Anisole (100-66-3) |
Description and Uses
Anisole is a colorless liquid with a spicy-sweet smell. Anisole can be produced by all the aforementioned methods. It is an important intermediate in the synthesis of organic compounds, for example fragrances and pharmaceuticals. The compound is also used as a solvent and as a heat transfer medium.
Anisole is widely used as a solvent for the synthesis of various organic compounds, anethole, nonylphenol isomer 4-(3',6'-dimethyl-3-heptyl)phenol, perfumes, insect pheromones and pharmaceuticals. It finds application in the preparation of inorganic complexes and materials such as tin-core/tin oxide nanoparticles.
Safety
| Symbol(GHS) |   GHS02,GHS07 |
| Signal word | Warning |
| Hazard statements | H226-H336 |
| Precautionary statements | P210-P233-P240-P241-P242-P243 |
| Hazard Codes | Xn,Xi |
| Risk Statements | 10-38-20-36/37 |
| Safety Statements | 37/39-26-16-24/25 |
| RIDADR | UN 2222 3/PG 3 |
| WGK Germany | 2 |
| RTECS | BZ8050000 |
| Autoignition Temperature | 887 °F |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | III |
| HS Code | 29093090 |
| Hazardous Substances Data | 100-66-3(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 3700 mg/kg (Taylor) |
