Home Categories Pharmaceutical intermediates 3-Amino-2-chloro-4-picoline
A0611812

3-Amino-2-chloro-4-picoline , 98% , 133627-45-9

CAS NO.:133627-45-9

Empirical Formula: C6H7ClN2

Molecular Weight: 142.59

MDL number: MFCD00673152

EINECS: 603-756-5

Pack Size Price Stock Quantity
1G RMB23.20 In Stock
5G RMB44.00 In Stock
25G RMB79.20 In Stock
100G RMB239.20 In Stock
500G RMB1095.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 65-70 °C
Boiling point: 283.3±35.0 °C(Predicted)
Density  1.260±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
solubility  Chloroform, Ethanol
pka 3.22±0.10(Predicted)
form  Crystals
color  Off White
InChI InChI=1S/C6H7ClN2/c1-4-2-3-9-6(7)5(4)8/h2-3H,8H2,1H3
InChIKey UOBCYTOUXLAABU-UHFFFAOYSA-N
SMILES C1(Cl)=NC=CC(C)=C1N

Description and Uses

3-Amino-2-chloro-4-methylpyridine, also known as CAPIC, is a key intermediate in the production of nevirapine, a non-nucleosidic reverse transcriptase inhibitor that has been established to be clinically useful for the treatment of infection by HIV-1.

Safety

Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P280-P301+P312+P330-P302+P352-P305+P351+P338+P310
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-41-37/38-22
Safety Statements  26-36/37/39-36-39
RIDADR  UN2811
WGK Germany  3
Hazard Note  Irritant
HazardClass  6.1
PackingGroup  III
HS Code  29333990

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