2-Acetylpyrazine , 99% , 22047-25-2

Synonym(s):
Acetylpyrazine

CAS NO.：22047-25-2

Empirical Formula: C6H6N2O

Molecular Weight: 122.12

MDL number: MFCD00006134

EINECS: 244-753-5

PRODUCT Properties

• Melting point: 76-78 °C (lit.)
• Boiling point: 78-79°C 8mm
• Density: 1.1075
• refractive index: 1.5350 (estimate)
• FEMA: 3126 | ACETYLPYRAZINE
• Flash point: 78-79°C/8mm
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Solid
• pka: 0.30±0.10(Predicted)
• color: White to Off-White
• Odor: popcorn-like odor
• Odor Type: popcorn
• JECFA Number: 784
• BRN: 109630
• InChIKey: DBZAKQWXICEWNW-UHFFFAOYSA-N
• LogP: 0.20

Description and Uses

2-acetylpyrazine is white to pale yellow crystalline powder with a nutty, popcorn, bread-crust odor. It is soluble in water and stable under ordinary conditions. It is used to manufacture many polycyclic compounds and used as useful structures in pharmaceuticals and perfumes. It is a component of the folates (vitamin B compounds) and of the isoalloxazine ring nucleus of flavins. Numerous pyrazine derivatives such as pyrazine polycyclic compounds, alkyl-, alicyclic-, and alkylaryl-substituted compounds, derivatives containing oxygenated functional groups and thio-functional groups in the side-chains are used in biological, drug, flavoring and perfumery industry. 2-acetylpyrazine is used as food additive, commonly used in chocolate and baked goods.

Acetylpyrazine has been used in synthesis of:
7-heteroaryl-pyrazolo[1,5-a]pyrimidine-3-carboxamides
copper (II) complexes with di-imine ligands
N(4) substituted thiosemicarbazones

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36-24/25
• WGK Germany: 2
• TSCA: T
• HazardClass: IRRITANT
• HS Code: 29339900