Home Categories Chemical pesticides DeltamethrinSolutioninAcetonitrile
A0597156

DeltamethrinSolutioninAcetonitrile , 1000μg/mLinAcetonitrile,uncertainty2%

Synonym(s):
(S)-α-Cyano-3-phenoxybenzyl(1R)- cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate;(S)-α-Cyano-3-phenoxybenzyl(1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate;Deltamethrin - CAS 52918-63-5 - Calbiochem

CAS NO.:

Empirical Formula: C22H19Br2NO3

Molecular Weight: 505.2

MDL number: MFCD00870122

EINECS: 258-256-6

Pack Size Price Stock Quantity
1.2ml RMB159.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 98°C
Boiling point: 300°C
alpha  +56~+64°(20℃/D)(c=4,C6H6)
Density  1.5214 (rough estimate)
vapor pressure  1.24×10-2Pa (25 °C)
refractive index  1.6220 (estimate)
Flash point: -18 °C
storage temp.  −20°C
solubility  Soluble in DMSO (up to 50 mg/ml)
Water Solubility  <0.0002 mg l-1 (25 °C)
form  Crystalline
color  Colorless
λmax 278nm(Hexane)(lit.)
Merck  14,2883
BRN  6746312
Stability: Stable. Incompatible with acids, alkalies, strong oxidizing agents.
LogP 6.200
IARC 3 (Vol. 53) 1991
NIST Chemistry Reference Deltamethrin(52918-63-5)
EPA Substance Registry System Deltamethrin (52918-63-5)

Description and Uses

Deltamethrin is a type II pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav). It binds to Drosophila para Nav channels in a use-dependent manner following brief depolarizing prepulses and with increasing concentrations of 1 to 5 nM, indicating that it preferentially binds to the channel in the open state. It slowly activates Nav1.8 channels, delays inactivation by longer than 40 ms, and induces persistent tail currents for channels expressed in X. laevis oocytes. Deltamethrin decreases proliferation of MCF-7 cells and inhibits androgen receptor transactivation when used at concentrations of 10 and 20 μM or greater, respectively. However, it is not cytotoxic to MCF-7 and CHO cells at concentrations of 25 and 100 μM, respectively, and does not induce transactivation of the estrogen receptor. Deltamethrin is lethal to mice with an LD50 value of 50 mg/kg and at low sublethal doses of 0.05 and 0.1 mg/kg it induces histopathological changes in the liver, kidney, spleen, and testes, including a loss of spermatozoa and Sertoli cells.

A Type II pyrethroid insecticide that potently inhibits calcineurin

Safety

Symbol(GHS) 
GHS06,GHS09
Signal word  Danger
Hazard statements  H301+H331-H410
Precautionary statements  P261-P264-P270-P273-P301+P310-P304+P340+P311
Hazard Codes  T,N,Xn,F
Risk Statements  23/25-50/53-67-65-38-11
Safety Statements  24-28-36/37/39-38-45-60-61-62-16
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  GZ1233000
HazardClass  6.1(a)
PackingGroup  II
HS Code  29269090
Hazardous Substances Data 52918-63-5(Hazardous Substances Data)
Toxicity LD50 in female rats (mg/kg): 31 orally; 4 i.v. (Kavlock)

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