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A0585250

Avibactamsodium , 98% , 1192491-61-4

CAS NO.:1192491-61-4

Empirical Formula: C7H10N3NaO6S

Molecular Weight: 287.226

MDL number: MFCD28900719

Pack Size Price Stock Quantity
25mg RMB63.20 In Stock
100mg RMB149.60 In Stock
250mg RMB224.00 In Stock
1g RMB631.20 In Stock
5g RMB1720.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: >208°C (dec.)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly, Heated, Sonicated), Water (Slightly, Sonicated)
form  Solid
color  White to Off-White
InChI InChI=1/C7H11N3O6S.Na.H/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);;/t4-,5+;;/s3
InChIKey JKMUNBAKQJMVKG-NLZGLQCHNA-N
SMILES C([C@@H]1CC[C@H]2N(OS(O)(=O)=O)C(=O)[N@@]1C2)(=O)N.[NaH] |&1:1,4,13,r|

Description and Uses

Avibactam sodium (NXL-104), a diazabicyclooctanone compound, is currently the most favoured novel β-lactamase inhibitor. Compared with the three marketed β-lactamase inhibitors, NXL-104 has a long duration of action and reversible covalent binding to the enzyme, and does not induce β-lactamase production.

Avibactam (NXL104) is a novel β-lactamase inhibitor with a non-lactam structural scaffold. NXL104 irreversibly inhibits lactamase from Mycobacterium tuberculosis.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H315-H335
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

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