LinoleicAcid,watersoluble
Synonym(s):
Linoleic acid;Linoleic Acid - CAS 60-33-3 - Calbiochem;Linolic Acid, cis,cis-9,12-Octadecadienoic Acid;Telfairic acid;cis,cis-9,12-Octadecadienoic Acid, Linolic Acid
CAS NO.：
Empirical Formula: C18H32O2
Molecular Weight: 280.45
MDL number: MFCD00064241
EINECS: 200-470-9
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB173.60 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | -5 °C (lit.) |
| Boiling point: | 229-230 °C/16 mmHg (lit.) |
| Density | 0.902 g/mL at 25 °C (lit.) |
| FEMA | 3380 | 9,12-OCTADECADIENOIC ACID (48%) AND 9,12,15-OCTADECATRIENOIC ACID (52%) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | NaOH: soluble1M |
| pka | 4.77(at 25℃) |
| form | liquid |
| color | Clear yellow |
| Odor | faint fatty |
| Water Solubility | INSOLUBLE |
| FreezingPoint | -5℃ |
| Sensitive | Air Sensitive |
| λmax | 270nm(H2O)(lit.) |
| JECFA Number | 332 |
| Merck | 14,5505 |
| BRN | 1727101 |
| Dielectric constant | 2.6（0℃） |
| Stability: | Stable, but air and light sensitive. Combustible. Incompatible with strong oxidizing agents. |
| InChIKey | OYHQOLUKZRVURQ-KQHSAVHASA-N |
| LogP | 7.050 |
| CAS DataBase Reference | 60-33-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 9,12-Octadecadienoic acid (Z,Z)-(60-33-3) |
| EPA Substance Registry System | Linoleic acid (60-33-3) |
Description and Uses
Linoleic acid is an essential ω-6 polyunsaturated fatty acid (PUFA). It is the most abundant PUFA in a variety of foods, and dietary sources of linoleic acid include vegetable oils, meats, nuts, seeds, and eggs. Linoleic acid (30 μM) increases migration of IEC-6 rat intestinal epithelial cells in a wound healing assay. Rats fed a linoleate-deficient diet exhibit decreased body weight and an increased ratio of eicosatrienoate to arachidonate in liver and serum phospholipids compared with rats fed a control diet, as well as mild scaling of forepaw skin.
Unsaturated μ-6 fatty acid Linoleic acid is involved in the production of quick-drying oils which are used in oil paints and varnishes. It is also used in beauty products due to its beneficial properties on the skin such as moisture retention. It is a key starting material for the synthesis of linoleyl alcohol and octadecanoic acid. It is used as a precursor of arachidonic acid (AA) and various prostaglandins. It may be used to improve the delivery and efficacy of anti-cancer drugs and in cancer protection.
Safety
| Symbol(GHS) |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225-H319 |
| Precautionary statements | P210-P305+P351+P338-P370+P378-P403+P235 |
| Hazard Codes | Xi |
| Risk Statements | 36-36/37/38 |
| Safety Statements | 26-24/25-36-37/39 |
| RIDADR | UN1170 - class 3 - PG 2 - Ethanol |
| WGK Germany | 1 |
| RTECS | RF9990000 |
| F | 8-10-23 |
| TSCA | Yes |
| HS Code | 29161500 |
| Hazardous Substances Data | 60-33-3(Hazardous Substances Data) |
| Toxicity | LD50 oral in mouse: > 50gm/kg |
