Tos-PEG4-Tos

Synonym(s):
2,2′-(Ethylenedioxy)diethyl ditosylate;Triethylene glycol ditosylate

CAS NO.：

Empirical Formula: C20H26O8S2

Molecular Weight: 458.55

MDL number: MFCD00048096

EINECS: 628-844-0

PRODUCT Properties

• Melting point: 78-82 °C(lit.)
• Boiling point: 534.03°C (rough estimate)
• Density: 1.3164 (rough estimate)
• refractive index: 1.6000 (estimate)
• storage temp.: Sealed in dry,Room Temperature
• solubility: Soluble in ethanol.
• form: powder to crystal
• color: White to Almost white
• BRN: 632509
• InChI: InChI=1S/C20H26O8S2/c1-17-3-7-19(8-4-17)29(21,22)27-15-13-25-11-12-26-14-16-28-30(23,24)20-9-5-18(2)6-10-20/h3-10H,11-16H2,1-2H3
• InChIKey: KCONMNWPRXAWKK-UHFFFAOYSA-N
• SMILES: C(OCCOS(C1=CC=C(C)C=C1)(=O)=O)COCCOS(C1=CC=C(C)C=C1)(=O)=O
• CAS DataBase Reference: 19249-03-7(CAS DataBase Reference)
• EPA Substance Registry System: Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-, bis(4-methylbenzenesulfonate) (19249-03-7)

Description and Uses

Tos-PEG4-Tos is a PEG linker containing two tosyl groups. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tri(ethylene glycol) di-p-toluenesulfonate is used in the synthesis of 1-[4-(1,4,7,10-tetraoxa-13-aza-cyclopentadec-13-yl)-phenyl] ethanone.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HS Code: 29093090